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Increased Virulence of Outer Membrane Porin Mutants of Mycobacterium abscessus

14 Jul 2021

Abstract excerpt

Chronic pulmonary infections caused by non-tuberculous mycobacteria of the Mycobacterium abscessus complex (MABSC) are emerging as a global health problem and pose a threat to susceptible individuals with structural lung disease such as cystic fibrosis. The molecular mechanisms underlying the pathogenicity and intrinsic resistance of MABSC to antibiotics remain largely unknown. The involvement of Msp-type porins...

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PMID: 34335541
DOI: 10.3389/fmicb.2021.706207

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