Article
Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2008
Fromont Gaelle, Yacoub Mokrane, Valeri Antoine, Mangin Philippe, Vallancien Guy, Cancel-Tassin Geraldine, Cussenot Olivier
Abstract excerpt
The hereditary predisposition to prostate cancer is rare and accounts for <5% of cases. Except for younger age at diagnosis, no phenotypic features have been clearly associated with hereditary prostate cancer. The aim of the study was to analyze the expression of genes related to androgen and estrogen metabolism in both hereditary and sporadic prostate cancers in patients matched for clinicopathologic features....
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