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Neurosurgery and pregnancy

16 Jun 2008

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortality in IPF patients. Matrix metalloproteinases (MMPs) are a large family of zinc-dependent endopeptidases, many of which have been implicated in the regulation of ECM degradation in lung...

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PMID: 18559459
DOI: 10.1136/jnnp.2007.117002

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