Article
Molecular analyses of GCH-1, TH and parkin genes in Chinese dopa-responsive dystonia families.
Clinical genetics - 1 Dec 2008
Wu Z-Y, Lin Y, Chen W-J, Zhao G-X, Xie H, Murong S-X, Wang N
Abstract excerpt
The symptomatic treatment of dopa-responsive dystonia (DRD) emphasizes the importance of molecular analyses of the GCH-1, TH and parkin genes. However, these analyses have not been extensively studied in Chinese DRD patients. Ten DRD families from the Han ethnic group including 14 patients and 28 clinically unaffected relatives were screened for GCH-1, TH and parkin mutations by direct sequencing,...
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