Article
Mutation negative "early-onset familial Alzheimer disease": consider screening for tau gene mutations.
Alzheimer disease and associated disorders - 1 Jan 2000
Larner Andrew J
Abstract excerpt
Mutations in 3 genes are known to be deterministic for early-onset familial Alzheimer disease. The genes are presenilin-1, presenilin-2, and amyloid precursor protein. As these genes prove to be negative in patients with a clinical diagnosis of early-onset familial Alzheimer disease, a search for...
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