Article
Issues in molecular genetic testing of individuals with suspected early-onset familial Alzheimer's disease.
Alzheimer disease and associated disorders - 1 Jan 1994
Karlinsky H, Sadovnick A D, Burgess M M, Langlois S, Hayden M R, Berg J M
Abstract excerpt
The identification of mutations in the amyloid precursor protein (APP) gene associated with the presence of early-onset familial Alzheimer disease (AD) raises the possibility of their practical clinical application, at least in some circumstances, in the diagnostic assessment for AD. As a stimulu...
Topics
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Genes, Dominant
- Genetic Counseling
- Genetic Testing
- Humans
- Male
- Middle Aged
- Mutation
- Neuropsychological Tests
- Risk Factors