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Article

Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium.

Journal of virology - 1 Aug 2008

Bartlett Emmalene J, Hennessey Margaret, Skiadopoulos Mario H, Schmidt Alexander C, Collins Peter L, Murphy Brian R, Pickles Raymond J

Abstract excerpt

Human parainfluenza virus type 1 (HPIV1) is a significant cause of pediatric respiratory disease in the upper and lower airways. An in vitro model of human ciliated airway epithelium (HAE), a useful tool for studying respiratory virus-host interactions, was used in this study to show that HPIV1 selectively infects ciliated cells within the HAE and that progeny virus is released from the apical surface with little...

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Identifiers

PMID: 18524813
DOI: 10.1128/JVI.02263-07
PMCID: PMC2519580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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