Article
Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells.
Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2008
Lord Matthew, Sladewski Thomas E, Pollard Thomas D
Abstract excerpt
Two functions are proposed for the conserved family of UCS proteins: helping to fold myosin motor proteins and stimulating the motor function of folded myosins. We examined both functions in yeast. The fission yeast UCS protein (Rng3p) concentrates in nodes containing myosin-II (Myo2) and other proteins that condense into the cytokinetic contractile ring. Both the N-terminal (central) and C-terminal (UCS) domains...
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