Article
Identification of a second, non-conserved amino acid that contributes to the unique sugar binding properties of the nematode galectin LEC-1.
Biological & pharmaceutical bulletin - 1 Jun 2008
Tamura Mayumi, Kasai Ken-ichi, Itagaki Takashi, Nonaka Takamasa, Arata Yoichiro
Abstract excerpt
The basic disaccharide structure recognized by galectin family members is the lactosamine-like structure Galbeta1-4(3)Glc(NAc). The 32-kDa galectin LEC-1 of the nematode Caenorhabditis elegans is composed of two domains, each of which is homologous to vertebrate 14-kDa-type galectins. The N-termi...
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