Article
Caenorhabditis elegans galectins LEC-6 and LEC-10 interact with similar glycoconjugates in the intestine.
The Journal of biological chemistry - 11 Feb 2011
Maduzia Lisa L, Yu Evan, Zhang Yinhua
Abstract excerpt
Galectins are a family of metazoan proteins that show binding to various β-galactoside-containing glycans. Because of a lack of proper tools, the interaction of galectins with their specific glycan ligands in the cells and tissues are largely unknown. We have investigated the localization of galectin ligands in Caenorhabditis elegans using a novel technology that relies on the high binding specificity between...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Galectins
- Glycoproteins
- Glycosylation
- Intestinal Mucosa
- Models, Biological
- Mutation
- Protein Binding
- Recombinant Proteins
