Article
Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation.
The American journal of psychiatry - 1 Jul 2008
Harvey Allison G
Abstract excerpt
Despite advances in the treatment of bipolar disorder, a significant proportion of patients experience disabling symptoms between episodes, and relapse rates are high. These circumstances suggest that there is a critical need to achieve a mechanistic understanding of triggers of relapse and to target them with specific, empirically derived treatments. Sleep disturbances are among the most prominent correlates of...
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