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Article

Use of xenofree matrices and molecularly-defined media to control human embryonic stem cell pluripotency: effect of low physiological TGF-beta concentrations.

Stem cells and development - 1 Jun 2008

Peiffer Isabelle, Barbet Romain, Zhou Yi-Ping, Li Ma-Lin, Monier Marie-Noëlle, Hatzfeld Antoinette, Hatzfeld Jacques A

Abstract excerpt

To monitor human embryonic stem cell (hESC) self-renewal without differentiation, we used quantitative RT-PCR to study a selection of hESC genes, including markers for self-renewal, commitment/differentiation, and members of the TGF-beta superfamily and DAN gene family. Indeed, low commitment/differentiation gene expression, together with a significant self-renewal gene expres sion, provides a better pluripotency...

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Source

Identifiers

PMID: 18513159
DOI: 10.1089/scd.2007.0279

Genes

CER1
GREM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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