Article
Association of polymorphisms at restriction enzyme recognition sites of apolipoprotein B and E gene with dyslipidemia in children undergoing primary nephrotic syndrome.
Molecular biology reports - 1 May 2009
Hu Peng, Qin Yuan Han, Jing Cheng Xue, Lei Feng Ying, Chen Ping, Li Ming Fang
Abstract excerpt
BACKGROUND: Dyslipidemia, a common complication, is very prevalent in children with primary nephrotic syndrome (PNS). Recent studies have shown that genetic basis may be involved in the onset of HLP secondary to PNS. ApoB and E have been identified as the important candidate genes for lipid abnormalities. OBJECTIVE: To investigate the association of apolipoprotein B (apoB) and E (apoE) genetic polymorphisms (Xba...
Topics
- Adolescent
- Apolipoproteins B
- Apolipoproteins E
- Case-Control Studies
- Child
- Child, Preschool
- DNA Restriction Enzymes
- Dyslipidemias
- Gene Frequency
- Genetic Predisposition to Disease