Article
Apolipoprotein E in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis.
Kidney international - 1 Feb 2003
Bruschi Maurizio, Catarsi Paolo, Candiano Giovanni, Rastaldi Maria Pia, Musante Luca, Scolari Francesco, Artero Mary, Carraro Michele, Carrea Alba, Caridi Gianluca, Zennaro Cristina, Sanna-Cherchi Simone, Viola Fabio Battista, Ferrario Franco, Perfumo Francesco, Ghiggeri Gian Marco
Abstract excerpt
BACKGROUND: Hyperlipemia characterizes nephrotic syndrome (NS) and contributes to the progression of the underlying nephropathy. The data in the literature support an implication of apolipoprotein E (apoE) in both hyperlipemia and focal segmental glomerulosclerosis (FSGS), a malignant condition associated with NS. METHODS: The apoE genotype was determined in 209 nephrotic patients, who were classified according...
Topics
- Adolescent
- Adult
- Apolipoproteins E
- Child
- Child, Preschool
- Cohort Studies
- Female
- Genotype
- Glomerulosclerosis, Focal Segmental
- Humans
- Kidney
- Male
- Nephrotic Syndrome