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Article

The yeast GID complex, a novel ubiquitin ligase (E3) involved in the regulation of carbohydrate metabolism.

Molecular biology of the cell - 1 Aug 2008

Santt Olivier, Pfirrmann Thorsten, Braun Bernhard, Juretschke Jeannette, Kimmig Philipp, Scheel Hartmut, Hofmann Kay, Thumm Michael, Wolf Dieter H

Abstract excerpt

Glucose-dependent regulation of carbon metabolism is a subject of intensive studies. We have previously shown that the switch from gluconeogenesis to glycolysis is associated with ubiquitin-proteasome linked elimination of the key enzyme fructose-1,6-bisphosphatase. Seven glucose induced degradation deficient (Gid)-proteins found previously in a genomic screen were shown to form a complex that binds FBPase. One...

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Identifiers

PMID: 18508925
DOI: 10.1091/mbc.e08-03-0328
PMCID: PMC2488282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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