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Disintegrins in health and disease

1 Jan 2008

Abstract excerpt

Few of the proteins isolated and characterized from snake venom have proven to be more chemically diverse, exquisitely specific or promiscuously active than the family known as disintegrins. These small proteins have shown structural homology with hundreds of cell surface molecules from plants and animals other than snakes, and their precise mimicry of native receptor ligands speaks to evolutionary niches related...

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PMID: 18508683
DOI: 10.2741/3177

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