Importance of a conserved hydrogen-bonding network in cytochromes c to their redox potentials and stabilities.

doi:10.1021/bi00231a002

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Article

Importance of a conserved hydrogen-bonding network in cytochromes c to their redox potentials and stabilities.

Biochemistry - 30 Apr 1991

Caffrey M S, Daldal F, Holden H M, Cusanovich M A

Abstract excerpt

To understand the determinants of redox potential and protein stability in c-type cytochromes, we have characterized two mutations to a highly conserved tyrosine group, tyrosine-75, of Rhodobacter capsulatus cytochrome c2. Mutant Y75F was designed to test the importance of the tyrosine hydroxyl g...

Topics

Circular Dichroism
Cytochrome c Group
Hydrogen
Mutation
Oxidation-Reduction
Photochemistry
Photosynthetic Reaction Center Complex Proteins
Rhodobacter capsulatus
Spectrophotometry, Ultraviolet
Tyrosine

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