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Article

Importance of a conserved hydrogen-bonding network in cytochromes c to their redox potentials and stabilities.

Biochemistry - 30 Apr 1991

Caffrey M S, Daldal F, Holden H M, Cusanovich M A

Abstract excerpt

To understand the determinants of redox potential and protein stability in c-type cytochromes, we have characterized two mutations to a highly conserved tyrosine group, tyrosine-75, of Rhodobacter capsulatus cytochrome c2. Mutant Y75F was designed to test the importance of the tyrosine hydroxyl group to the typically high redox potentials of the cytochromes c2 while maintaining a hydrophobic core. Mutant Y75C was...

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Identifiers

PMID: 1850617
DOI: 10.1021/bi00231a002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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