Article
Impact of genetics on low bone mass in adults.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2008
Sigurdsson Gunnar, Halldorsson Bjarni V, Styrkarsdottir Unnur, Kristjansson Kristleifur, Stefansson Kari
Abstract excerpt
Low bone mass in adults is a major risk factor for low-impact fractures and is considered of complex origin because of interaction of environmental and genetic factors, each with modest effect. The objective was to assess the relative impact of genetics and environment and quantify the risk in relatives of osteopenic individuals. We studied 440 Icelandic nuclear families with 869 first-degree relatives of both...
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