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Article

Bare nanocapillary for DNA separation and genotyping analysis in gel-free solutions without application of external electric field.

Analytical chemistry - 15 Jul 2008

Wang Xiayan, Wang Shili, Veerappan Vijaykumar, Byun Chang Kyu, Nguyen Han, Gendhar Brina, Allen Randy D, Liu Shaorong

Abstract excerpt

In this work, we demonstrate DNA separation and genotyping analysis in gel-free solutions using a nanocapillary under pressure-driven conditions without application of an external electric field. The nanocapillary is a approximately 50-cm-long and 500-nm-radius bare fused-silica capillary. After a DNA sample is injected, the analytes are eluted out in a chromatographic separation format. The elution order of DNA...

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Identifiers

PMID: 18500828
DOI: 10.1021/ac800549k
PMCID: PMC2706485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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