Article
Development of a large-scale de-identified DNA biobank to enable personalized medicine.
Clinical pharmacology and therapeutics - 1 Sept 2008
Roden D M, Pulley J M, Basford M A, Bernard G R, Clayton E W, Balser J R, Masys D R
Abstract excerpt
Our objective was to develop a DNA biobank linked to phenotypic data derived from an electronic medical record (EMR) system. An "opt-out" model was implemented after significant review and revision. The plan included (i) development and maintenance of a de-identified mirror image of the EMR, namely, the "synthetic derivative" (SD) and (ii) DNA extracted from discarded blood samples and linked to the SD. Surveys...
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