Article
A familial occurrence of natural killer cell--T-lymphocyte proliferation disease in two children.
Cancer - 15 May 1991
Le Deist F, de Saint Basile G, Coulombel L, Breton-Gorius J, Maier-Redelsperger M, Beljorde K, Bremard C, Griscelli C
Abstract excerpt
Several reports describe the association of hyperlymphocytosis with neutropenia. This syndrome, named lymphoproliferative disease, is characterized by a chronic indolent clinical course, bone marrow lymphocyte infiltration, and granulopenia of central origin. The proliferating lymphocytes share l...
Topics
- Adolescent
- Agranulocytosis
- Antigens, Differentiation, T-Lymphocyte
- Cell Nucleus
- Family
- Female
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Hematopoietic Stem Cells
- Humans
- Killer Cells, Natural
- Leukocyte Count
- Lymphoproliferative Disorders
- Male
- Phenotype
- T-Lymphocytes