Article
Novel variants in UBE2B gene and idiopathic male infertility.
Journal of andrology - 1 Jan 2000
Suryavathi Viswanadhapalli, Khattri Arun, Gopal Kaliappan, Rani Deepa Selvi, Panneerdoss Subbarayalu, Gupta Nalini J, Chakravarty Baidyanath, Deenadayal Mamta, Singh Lalji, Thangaraj Kumarasamy
Abstract excerpt
The UBE2B gene encodes ubiquitin-conjugating enzyme, which is involved in DNA repair. Ube2b knockout mice were found to be infertile because of structural abnormality of sperm. However, there is no genetic study on the role of the UBE2B gene in human fertility; therefore, the present investigation was designed to study genetic variations in the UBE2B gene and its role in human male infertility. Sequence analyses...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
