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Article

[UBE2B gene and male infertility: an update].

Zhonghua nan ke xue = National journal of andrology - 1 Apr 2014

Zhang Qiang, Mou Li-Sha, Gui Yao-Ting, Cai Zhi-Ming

Abstract excerpt

Male infertility is a worldwide problem, and about 15% of the cases are associated with spermatogenesis-related gene mutation. The mammalian gene UBE2B is the homolog of the RAD6 gene of yeast, belonging to the ubiquitin proteasome system and playing an important role in spermatogenesis. Mice lacking the UBE2B gene are infertile, with reduced sperm motility, increased morphologically abnormal sperm, and inhibited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24873167

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