Article
Anti-PGL-Tb1 responses as an indicator of the immune restoration syndrome in HIV-TB patients.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2008
Simonney N, Dewulf G, Herrmann J-L, Gutierrez M C, Vicaut E, Boutron C, Leportier M, Lafaurie M, Abgrall S, Sereni D, Autran B, Carcelain G, Bourgarit A, Lagrange P H
Abstract excerpt
A prospective and multi-centre study has allowed us to analyse antibody responses and Mycobacterium tuberculosis clinical isolate genotypes on 24 consecutive HIV-TB co-infected patients treated with Highly Active Antiretroviral Therapy (HAART) who either went on to develop a TB Immune Restoration Syndrome (TB-IRS), or not. Circulating free and immune-complexed antibodies against ManLAM, ESAT-6/CFP10 and PGL-Tb1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
