Robustness of maximum likelihood tree estimation against different patterns of base substitutions.

Abstract excerpt

In the maximum likelihood (ML) method for estimating a molecular phylogenetic tree, the pattern of nucleotide substitutions for computing likelihood values is assumed to be simpler than that of the actual evolutionary process, simply because the process, considered to be quite devious, is unknown. The problem, however, is that there has been no guarantee to endorse the simplification. To study this problem, we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Base Composition
• Share to Computer Simulation
• Share to Models, Genetic