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Article

Robustness of coalescent estimators to between-lineage mutation rate variation.

Molecular biology and evolution - 1 Dec 2006

Kuhner Mary K

Abstract excerpt

Data from HIV and from human neoplastic cells can show substantial between-lineage mutation rate variation even within a single population. Such variation may affect estimators of population quantities such as Theta = 4N(e)mu. Using simulated DNA data, I measured the effect of rate variation on recovery of Theta by the summary-statistic estimator of Watterson (Watterson GA. 1975. On the number of segregating...

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PMID: 16956973
DOI: 10.1093/molbev/msl106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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