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Article

Optimization of an effective directed differentiation medium for differentiating mouse bone marrow mesenchymal stem cells into hepatocytes in vitro.

Cell biology international - 1 Aug 2008

Shi Xiao-Lei, Mao Liang, Xu Bi-Yun, Xie Ting, Zhu Zhang-Hua, Chen Jun-Hao, Li Lei, Ding Yi-Tao

Abstract excerpt

We have used a uniform design to explore the most effective directed differentiation medium (MEDDM) for differentiating mouse bone marrow mesenchymal stem cells (mMSCs) into hepatocytes. Our methods involved arranging eight differentiation medium groups following uniform design. Flow cytometry was used to evaluate the percentage of ALB+ and CK18+ cells in each group. Factors and their concentrations in the MEDDMs...

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PMID: 18486499
DOI: 10.1016/j.cellbi.2008.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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