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Newcastle disease virus: Detection and characterization by PCR of recent German isolates differing in pathogenicity

1 Jun 1998

Abstract excerpt

The fusion (F) protein plays an important role in determining the virulence of Newcastle disease virus (NDV) strains. A reverse transcriptase-polymerase chain reaction (RT-PCR) is described which amplifies a 362 bp fragment encompassing the region of the F protein most important for pathogenicity. A specific PCR product was obtained independent of strain, pathogenicity and host of origin. Sequencing of the region...

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PMID: 18483993
DOI: 10.1080/03079459808419330

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