Article
Single nucleotide polymorphisms in the apo(a) kringle IV type 8 domain are not associated with atherothrombotic serum lipoprotein (a) concentration, in a Portuguese paediatric population.
International journal of laboratory hematology - 1 Jun 2008
Ferreira H, Costa E, Vieira E, Barbot J, Dos Santos R
Abstract excerpt
Lipoprotein (a) (Lp[a]) is a complex of apolipoprotein (a) (apo[a]) and low-density lipoprotein (LDL), associated with atherothrombotic disease. Most of the interindividual variations in plasma levels of Lp(a) can be attributed to sequence differences linked to the apo(a) gene locus. The aim of t...
Topics
- Adolescent
- Apolipoproteins A
- Base Sequence
- Case-Control Studies
- Child
- Child, Preschool
- Exons
- Female
- Genetic Predisposition to Disease
- Humans
- Introns
- Male