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Article

The Yersinia adhesin YadA binds to a collagenous triple-helical conformation but without sequence specificity.

Protein engineering, design & selection : PEDS - 1 Aug 2008

Leo Jack C, Elovaara Heli, Brodsky Barbara, Skurnik Mikael, Goldman Adrian

Abstract excerpt

The Yersinia adhesin A (YadA) is a collagen-binding trimeric autotransporter of Yersinia enterocolitica, an enteropathogen that causes a range of gastroenteric and systemic diseases, and YadA is essential for Y. enterocolitica virulence. Although previous studies suggest a specific binding site in collagen for YadA, we found that recombinant YadA binds to both major cyanogen bromide fragments of collagen type II...

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Identifiers

PMID: 18467342
DOI: 10.1093/protein/gzn025
PMCID: PMC3254170

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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