Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation

Abstract excerpt

Although chronological donor age is the most potent predictor of long-term outcome after renal transplantation, it does not incorporate individual differences of the aging-process itself. We therefore hypothesized that an estimate of biological organ age as derived from markers of cellular senescence in zero hour biopsies would be of higher predictive value. Telomere length and mRNA expression levels of the cell...

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• Share to Cytomegalovirus and herpesvirus research
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