Article
[-2548G/A functional polymorphism in the promoter region of leptin gene and antipsychotic agent-induced weight gain in schizophrenic patients: a study of nuclear family-based association].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Apr 2008
Mou Xiao-dong, Zhang Zhi-jun, Zhang Xiang-rong, Shi Jia-bo, Sun Jing
Abstract excerpt
OBJECTIVE: To investigate whether there is association between the-2548G/A functional polymorphism in the promoter region of leptin gene and weight gain following antipsychotic agents (APS) acute treatment in schizophrenic patients. METHODS: Eight-four Chinese Han untreated schizophrenia patients in 70 nuclear families were recruited. The polymorphism of leptin gene was determined with PCR-RFLP technique. Body...
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