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Article

The Genomic Grade Assay Compared With Ki67 to Determine Risk of Distant Breast Cancer Recurrence.

JAMA oncology - 1 Feb 2016

Ignatiadis Michail, Azim Hatem A, Desmedt Christine, Veys Isabelle, Larsimont Denis, Salgado Roberto, Lyng Maria B, Viale Giuseppe, Leyland-Jones Brian, Giobbie-Hurder Anita, Kammler Rosita, Dell'Orto Patrizia, Rothé Françoise, Laïos Ioanna, Ditzel Henrik J, Regan Meredith M, Piccart Martine, Michiels Stefan, Sotiriou Christos

Abstract excerpt

IMPORTANCE: The Genomic Grade Index (GGI) was previously developed, evaluated on frozen tissue, and shown to be prognostic in early breast cancer. To test the GGI in formalin-fixed, paraffin-embedded breast cancer tumors, a quantitative reverse transcriptase polymerase chain reaction assay was developed and named the Genomic Grade (GG). The GG assay has the potential to increase the clinical application of the...

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Identifiers

PMID: 26633571
DOI: 10.1001/jamaoncol.2015.4377

Genes

ERBB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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