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Article

Gene structure evolution of the Na+-Ca2+ exchanger (NCX) family.

BMC evolutionary biology - 30 Apr 2008

On Caly, Marshall Christian R, Chen Nansheng, Moyes Christopher D, Tibbits Glen F

Abstract excerpt

BACKGROUND: The Na+-Ca2+ exchanger (NCX) is an important regulator of cytosolic Ca2+ levels. Many of its structural features are highly conserved across a wide range of species. Invertebrates have a single NCX gene, whereas vertebrate species have multiple NCX genes as a result of at least two duplication events. To examine the molecular evolution of NCX genes and understand the role of duplicated genes in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18447948
DOI: 10.1186/1471-2148-8-127
PMCID: PMC2408596

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