Article
On the potential for extinction by Muller's ratchet in Caenorhabditis elegans.
BMC evolutionary biology - 30 Apr 2008
Loewe Laurence, Cutter Asher D
Abstract excerpt
BACKGROUND: The self-fertile hermaphrodite worm C. elegans is an important model organism for biology, yet little is known about the origin and persistence of the self-fertilizing mode of reproduction in this lineage. Recent work has demonstrated an extraordinary degree of selfing combined with a high deleterious mutation rate in contemporary populations. These observations raise the question as to whether the...
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