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Article

Angiotensin converting enzyme insertion/deletion genotype is associated with leukoaraiosis in lacunar syndromes.

Journal of neurology, neurosurgery, and psychiatry - 1 Mar 2002

Hassan A, Lansbury A, Catto A J, Guthrie A, Spencer J, Craven C, Grant P J, Bamford J M

Abstract excerpt

OBJECTIVES: Pathological and clinical data suggest that patients presenting with ischaemic lacunar syndromes may be a heterogenous group. Those with isolated lacunar infarction are thought to have localised atherosclerosis whereas in those with coexisting leukoaraiois a distinct diffuse small vessel vasculopathy may be the predominant underlying pathology. The ACE insertion/deletion (I/D) polymorphism is an...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11861692
DOI: 10.1136/jnnp.72.3.343
PMCID: PMC1737772

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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