Article
The mych gene is required for neural crest survival during zebrafish development.
PloS one - 30 Apr 2008
Hong Sung-Kook, Tsang Michael, Dawid Igor B
Abstract excerpt
BACKGROUND: Among Myc family genes, c-Myc is known to have a role in neural crest specification in Xenopus and in craniofacial development in the mouse. There is no information on the function of other Myc genes in neural crest development, or about any developmental role of zebrafish Myc genes. PRINCIPAL FINDINGS: We isolated the zebrafish mych (myc homologue) gene. Knockdown of mych leads to severe defects in...
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