Article
Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: a randomized, controlled study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Apr 2008
McComsey G A, Lo Re V, O'Riordan M, Walker U A, Lebrecht D, Baron E, Mounzer K, Frank I
Abstract excerpt
BACKGROUND: Stavudine is widely used in developing countries. Lipoatrophy and mitochondrial toxicity have been linked to stavudine use, but it is unclear whether switching to a lower dose can reduce these toxicities while maintaining human immunodeficiency virus (HIV) suppression. METHODS: HIV-in...
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