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Article

Potential role of miR-9 and miR-223 in recurrent ovarian cancer

28 Apr 2008

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene expression by binding to target mRNAs. miRNAs have not been comprehensively studied in recurrent ovarian cancer, yet an incurable disease. RESULTS: Using real-time RT-PCR, we obtained distinct miRNA expression profiles between primary and recurrent serous papillary ovarian adenocarcinomas (n = 6) in a subset of samples...

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PMID: 18442408
DOI: 10.1186/1476-4598-7-35

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