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Article

Successful treatment of carcinomatous meningitis with gefitinib in a patient with lung adenocarcinoma harboring a mutated EGF receptor gene.

The Tohoku journal of experimental medicine - 1 Apr 2008

Fukuhara Tatsuro, Saijo Yasuo, Sakakibara Tomohiro, Inoue Akira, Morikawa Naoto, Kanamori Masayuki, Nakashima Ichiro, Nukiwa Toshihiro

Abstract excerpt

Carcinomatous meningitis is a severe complication of lung cancer. Although treatment with gefitinib, a tyrosine kinase inhibitor of epidermal growth factor (EGF) receptor, has been reported to be highly effective against lung cancers harboring a mutated EGF gene, its effect against carcinomatous meningitis is unknown. Here, we report successful treatment of carcinomatous meningitis with gefitinib in a lung cancer...

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Source

Identifiers

PMID: 18441512
DOI: 10.1620/tjem.214.359

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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