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Article

Characteristics of linkage disequilibrium in North American Holsteins.

BMC genomics - 8 Jul 2010

Bohmanova Jarmila, Sargolzaei Mehdi, Schenkel Flavio S

Abstract excerpt

BACKGROUND: Effectiveness of genomic selection and fine mapping is determined by the level of linkage disequilibrium (LD) across the genome. Knowledge of the range of genome-wide LD, defined as a non-random association of alleles at different loci, can provide an insight into the optimal density and location of single-nucleotide polymorphisms (SNPs) for genome-wide association studies and can be a keystone for...

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PMID: 20609259
DOI: 10.1186/1471-2164-11-421
PMCID: PMC2996949

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