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Article

Serum-induced iron-acquisition systems and TonB contribute to virulence in Klebsiella pneumoniae causing primary pyogenic liver abscess.

The Journal of infectious diseases - 15 Jun 2008

Hsieh Pei-Fang, Lin Tzu-Lung, Lee Cha-Ze, Tsai Shih-Feng, Wang Jin-Town

Abstract excerpt

BACKGROUND: Klebsiella pneumoniae has become the predominant pathogen causing primary pyogenic liver abscess (PLA). METHODS: K. pneumoniae was stimulated by human serum, and gene expression was analyzed by microarray. RESULTS: Three putative iron acquisition systems, Yersinia high-pathogenicity island (HPI), iucABCDiutA, and iroA(iroNDCB), that increased in expression and predominated in PLA-associated K....

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PMID: 18433330
DOI: 10.1086/588383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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