Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

First genetic analysis in Tunisian familial adenomatous polyposis probands.

Oncology reports - 1 May 2008

Bougatef Karim, Marrakchi Raja, Moussa Amel, Blondeau-Lahely Yannick, Najjar Tawfik, Coulet Florence, Colas Chrystelle, Ben Ayed Farhat, Ben Ammar Elgaaied Amel, Soubrier Florent

Abstract excerpt

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the development of hundreds to thousands of adenomatous polyps in colon and rectum. The APC gene (adenomatous polyposis coli) is considered as the major mutated gene in FAP. It has been shown that biallelic germline mutations in the base-excision-repair gene MYH can be responsible for a recessive inheritance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, APC

Share to Germ-Line Mutation

Share to Introns

Share to Models, Genetic

Share to Tunisia

Source

Identifiers

PMID: 18425378

Genes

APC
FAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

First genetic analysis in Tunisian familial adenomatous polyposis probands.PMID 18425378Read ↗

Do we know all there is to know about Familial Adenomatous Polyposis?Semantic proximity Read ↗

Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.Semantic proximity Read ↗

MUTYH-Associated Polyposis: The Irish Experience>.Semantic proximity Read ↗

Molecular analysis of the APC and MYH genes in Czech families affected by FAP or multiple adenomas: 13 novel mutations.Semantic proximity Read ↗

The first mutations in the MYH gene reported in Moroccan colon cancer patients.Semantic proximity Read ↗

Familial adenomatous polyposis: genetics and epidemiology.Semantic proximity Read ↗

Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients.Semantic proximity Read ↗

Implication of MYH in Colorectal PolyposisSemantic proximity Read ↗

First description of mutational analysis of MLH1, MSH2 and MSH6 in Algerian families with suspected Lynch syndrome.Semantic proximity Read ↗

Prevalence of MYH-associated polyposis related to three recurrent mutations in Morocco.Semantic proximity Read ↗

[Hereditary forms of colorectal adenomatous polyposis].Semantic proximity Read ↗

Type and frequency of MUTYH variants in Italian patients with suspected MAP: a retrospective multicenter study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.