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Article

A protein complex in the brush-border membrane explains a Hartnup disorder allele.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2008

Kowalczuk Sonja, Bröer Angelika, Tietze Nadine, Vanslambrouck Jessica M, Rasko John E J, Bröer Stefan

Abstract excerpt

Protein absorption in the intestine is mediated by proteases and brush-border peptidases together with peptide and amino acid transporters. Neutral amino acids are generated by a variety of aminopeptidases and carboxypeptidases and are subsequently taken up by the amino acid transporter B(0)AT1 (SLC6A19), which is mutated in Hartnup disorder. Coexpression of B(0)AT1 together with the brush-border carboxypeptidase...

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Share to Amino Acid Transport Systems, Neutral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18424768
DOI: 10.1096/fj.08-107300

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A protein complex in the brush-border membrane explains a Hartnup disorder allele.PMID 18424768Read ↗

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