Article
Culture‐Negative Intracerebral Abscesses in Children and Adolescents fromStreptococcus anginosusGroup Infection: A Case Series
4 Apr 2008
Abstract excerpt
We report the use of 16S ribosomal RNA gene amplification and sequencing to diagnose culture-negative intracerebral abscesses in younger patients. These 3 cases demonstrate the optimal application of gene sequencing from direct specimens for patients with negative culture results compromised by antibacterial therapy but histories highly suggestive of acute bacterial infection.
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