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Article

Henipavirus V protein association with Polo-like kinase reveals functional overlap with STAT1 binding and interferon evasion.

Journal of virology - 1 Jul 2008

Ludlow Louise E, Lo Michael K, Rodriguez Jason J, Rota Paul A, Horvath Curt M

Abstract excerpt

Emerging viruses in the paramyxovirus genus Henipavirus evade host antiviral responses via protein interactions between the viral V and W proteins and cellular STAT1 and STAT2 and the cytosolic RNA sensor MDA5. Polo-like kinase (PLK1) is identified as being an additional cellular partner that can bind to Nipah virus P, V, and W proteins. For both Nipah virus and Hendra virus, contact between the V protein and the...

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Share to Fluorescent Antibody Technique, Indirect
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18417573
DOI: 10.1128/JVI.00409-08
PMCID: PMC2447080

Genes

PLK1
STAT1
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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