Article
PLAP-1/asporin inhibits activation of BMP receptor via its leucine-rich repeat motif.
Biochemical and biophysical research communications - 27 Jun 2008
Tomoeda M, Yamada S, Shirai H, Ozawa Y, Yanagita M, Murakami S
Abstract excerpt
We previously identified the novel gene, periodontal ligament-associated protein-1 (PLAP-1)/asporin and reported that PLAP-1/asporin inhibited bone morphogenetic protein-2 (BMP-2)-induced cytodifferentiation of periodontal ligament (PDL) cells probably by direct interaction with BMP-2. Here, we elucidated the detailed regulatory mechanism of this protein on BMP-2-induced cytodifferentiation of PDL cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.