Article
Polymorphisms of TNF-alpha and LT-alpha genes in multiple myeloma.
Leukemia research - 1 Oct 2008
Kádár Katalin, Kovács Margit, Karádi István, Melegh Béla, Pocsai Zsuzsa, Mikala Gábor, Tordai Attila, Szilágyi Agnes, Adány Róza, Füst George, Várkonyi Judit
Abstract excerpt
Allelic distribution of -308 G>A (TNF 1/2) polymorphism of the TNF-alpha, and the +252 A>G promoter polymorphism of the LT-alpha gene, the 1267 A>G polymorphism of the HSP70-2 gene as well as the -429 T>C promoter polymorphism of the RAGE gene were tested in 94 MM cases and 141 controls. Significantly less MM patients than controls carried the TNF2 allele (p=0.018) and the TNF2-LTA 252G haplotype (p=0.025). The...
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