Article
Polymorphisms in 9q32 and TSCOT are linked to cervical cancer in affected sib-pairs with high mean age at diagnosis.
Human genetics - 1 Jun 2008
Engelmark Malin T, Ivansson Emma L, Magnusson Jessica J, Gustavsson Inger M, Wyöni Per-Ivan, Ingman Max, Magnusson Patrik K E, Gyllensten Ulf B
Abstract excerpt
Cervical cancer is a multifactorial disease influenced by both environmental and genetic factors. We have previously found linkage to 9q32 in a genomewide scan of affected sib-pairs (ASPs) with cervical cancer and to the thymic stromal co-transporter (TSCOT), a candidate gene in this region. Here we examined the contribution of 9q32 and TSCOT to cervical cancer susceptibility using at larger material of 641 ASPs,...
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