Article
Prevalence of high-risk alleles in the LOXL1 gene and its association with pseudoexfoliation syndrome and exfoliation glaucoma in a Latin American population.
Ophthalmic genetics - 1 Mar 2012
Jaimes Martha, Rivera-Parra David, Miranda-Duarte Antonio, Valdés Gerardo, Zenteno Juan Carlos
Abstract excerpt
PURPOSE: Pseudoexfoliation syndrome (XFS) is a major risk factor for exfoliation glaucoma (XFG). A significant association exists between XFG and several SNPs in the lysyl oxidase-like 1 (LOXL1) gene. The purpose of this study was to report the results of the first association study between LOXL1 polymorphisms and XFS and/or XFG in a Latin American population. METHODS: Genotypes of three high-risk SNPs of LOXL1...
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